01 - Preheat oven to 425°F. Line a baking sheet with parchment paper.
02 - Toss cauliflower florets with olive oil, salt, and pepper. Spread evenly on the prepared baking sheet.
03 - Roast for 25 to 30 minutes, flipping halfway, until cauliflower is golden and tender with crispy edges.
04 - While cauliflower roasts, mix mayonnaise, sour cream, chili powder, smoked paprika, garlic powder, and lime juice in a large bowl.
05 - When cauliflower is done, immediately transfer to the bowl with sauce. Toss to coat thoroughly.
06 - Add half the cotija cheese, half the cilantro, red onion, and jalapeño. Toss again to combine.
07 - Transfer to a serving platter. Sprinkle with remaining cotija, extra chili powder, and cilantro. Serve warm with lime wedges.