01 - Heat a large skillet over medium-high heat. Add the ground beef, season with salt, pepper, garlic powder, and onion powder. Cook, breaking the meat apart with a spoon, until fully browned and no pink remains, about 6 to 8 minutes. Drain excess fat if needed.
02 - While the beef cooks, divide the chopped romaine lettuce among 4 serving bowls. Top each with cherry tomatoes, diced red onion, sliced pickles, and shredded cheddar cheese.
03 - In a small mixing bowl, whisk together the mayonnaise, ketchup, yellow mustard, sweet relish, paprika, and white vinegar until smooth and well combined. Taste and adjust seasoning as desired.
04 - Divide the cooked ground beef evenly among the 4 prepared salad bowls, layering it over the vegetables and cheese.
05 - Generously spoon the burger sauce over each bowl, ensuring even coverage across the beef and vegetables.
06 - Finish with your choice of optional toppings such as crumbled bacon, sliced avocado, jalapeño slices, or sesame seeds. Serve immediately while the beef is warm.